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R-R-1854 Cearoin CAS No.52811-37-7 Cearoin/CAS No.52811-37-7 increases autophagy and apoptosis through the production of ROS and the activation of ERK. price>
R-CG-031 PLGA-S-S-PEG-OH Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-hydroxyl,PLGA-S-S-PEG-OH from ruixi.PLGA is connected with disulfide bond, then peg hydroxyl (PEG OH) is coupled to form plga-s-s-peg-OH. The product can be used to prepare micelles or vesicles and other new targeted products for drug encapsulation. price>
R-M-485 Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-NH₂ (Disulfide bond) The potent anticoagulant E-76, Acetyl-ALCDDPRVDRWYCQFVEG-amide, is an inhibitor of coagulation factor VIIa. It has been suggested that E-76 works by binding to an exosite on the factor VIIa protease domain, and non-competitively inhibits activation of factor X and amidolytic activity. E-76 has a well defined structure in solution determined by NMR spectroscopy that is similar to the X-ray crystal structure when complexed with factor VIIa and represents a new framework for the development of inhibitors for serine proteases. price>
R-M-702 Buccalin trifluoroacetate salt This modulatory neuropeptide has been colocalized with the small cardioactive peptides A and B to a single cholinergic motor neuron of Aplysia californica. Unlike the small cardioactive peptides, it seems to act presynaptically on the nerve terminals to inhibit acetylcholine release. price>
R-R-1855 PD173952 CAS No.305820-75-1 PD173952/CAS No.305820-75-1 is a tyrosine kinases inhibitor with IC50s of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk, respectively. PD173952 is also a potent Myt1 kinase inhibitor with a Ki of 8.1 nM. PD173952 induces apoptosis. price>
R-CG-032 PLGA-S-S-PEG-CHO Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-CHO,PLGA-S-S-PEG-CHO from ruixi.PLGA is connected with disulfide bond, then peg CHO (PEG CHO) is coupled to form plga-s-s-peg-CHO. The product can be used to prepare micelles or vesicles and other new targeted products for drug encapsulation. price>
R-M-486 Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH₂ trifluoroacetate salt (Disulfid Full competitive MCH-1 receptor antagonist devoid of agonist potency for the human MCH-1 receptor even at micromolar concentrations (Kb = 3.6 nM). price>
R-M-703 Astressin trifluoroacetate salt Astressin trifluoroacetate salt ,CAS: 170809-51-5 from ruixi.The Glu³⁰ to Lys³³ lactam bridge constrains astressin in an α-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than α-helical CRF (9-41) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date. price>
R-R-1856 Indibulin CAS No.204205-90-3 Indibulin (ZIO 301)/CAS No.204205-90-3, an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis. price>
R-CG-033 PLGA-S-S-PEG-Fitc Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-fluorescence ,PLGA-S-S-PEG-Fitc from ruixi.PLGA is connected with disulfide bond, then peg Fitc (PEG Fitc) is coupled to form plga-s-s-peg-Fitc. The product can be used to prepare micelles or vesicles and other new targeted products for drug encapsulation. price>
R-M-704 Atosiban acetate salt Atosiban acetate salt (CAS :90779-69-4) is a vasopressin receptor antagonist. price>
R-R-1857 Mepazine CAS No.60-89-9 Mepazine (Pecazine)/CAS No.60-89-9 is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis. price>
R-CG-034 PLGA-SS-PEG-Rhodamine B(RhB) Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-Rhodamine B(RhB),PLGA-SS-PEG-Rhodamine B(RhB) from ruixi.PLGA is connected with disulfide bond, then peg Rhodamine B(RhB)(PEG Rhodamine B(RhB) is coupled to form plga-s-s-peg-Rhodamine B(RhB).The product can be used to prepare micelles or vesicles and other new targeted products for drug encapsulation. price>
R-M-705 Atosiban (free acid) trifluoroacetate salt Atosiban (free acid) trifluoroacetate salt(CAS : 168102-69-0) is a Impurity and degradation product of atosiban. price>
R-R-1858 Gemcitabine-13C,15N2 hydrochloride CAS No.2757566-59-7 Gemcitabine-13C,15N2 (hydrochloride)/CAS No.2757566-59-7 is the 13C and 15N labeled Gemcitabine hydrochloride. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis. price>
R-CG-035 PLGA-Hydrazone(hyd)-PEG-SH Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-SH,PLGA-SS-PEG-thiol from ruixi.Hydrazone bond has pH response effect. DSPE was linked to hydrazone bond and PEG thiol was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-R-1859 Mepazine hydrochloride CAS No.2975-36-2 Mepazine hydrochloride (Pecazine hydrochloride)/CAS No.2975-36-2 is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine hydrochloride affects viability of ABC-DLBCL cells by enhancing apoptosis. price>
R-CG-036 PLGA-Hydrazone(Hyd)-PEG-Azide(N3) Poly(L-lactide-co-glycolide)-Hydrazone-Polyethylene glycol-Azide(N3),PLGA-Hyd-PEG-Azide(N3) from ruixi.Hydrazone bond has pH response effect. PLGA was linked to hydrazone bond and PEG Azide was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells. price>
R-M-707 BQ-788 sodium salt BQ-788 sodium salt,CAS :156161-89-6 from ruixi.It is a synthetic peptide. price>
R-R-1860 Bufarenogin CAS No.17008-65-0 Bufarenogin/CAS No.17008-65-0 induces intrinsic apoptosis via Bax and ANT cooperation. price>