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Catalog	name	Description	price
R-C-642	PD153035HCl CAS No. 183322-45-4	PD153035 HCl(SU-5271 HCl,AG1517 HCl,ZM 252868 HCl) is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR,FGFR,CSF-1,InsR and Src.	price>
R-R-2342	(R,R)-VVD-118313 CAS No.2875046-31-2	(R,R)-VVD-118313/CAS No.2875046-31-2 is the isomer of VVD-118313 (HY-151385). VVD-118313 is a selective JAK1 inhibitor and blocks JAK1-dependent trans-phosphorylation and cytokine signaling. VVD-118313 can be used for research of cancer. (R,R)-VVD-118313 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-643	BIX02188 CAS:1094614-84-2	BIX02188 is a potent MEK5-selective inhibitor with an IC50 of 4.3 nM.BIX02188 inhibits ERK5 catalytic activity,with an IC50 of 810 nM.	price>
R-R-2343	GDC-4379 CAS No.2252277-73-7	GDC-4379/CAS No.2252277-73-7 is a JAK1 inhibitor that can be used for the research of asthma.	price>
R-C-644	BIX02189 CAS:1094614-85-3	BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM,also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays,and does not inhibit closely related kinases MEK1,MEK2,ERK2,and JNK2.	price>
R-R-2344	Tubulin/JAK2-IN-1 CAS No.2933938-46-4	Tubulin/JAK2-IN-1 (compound 7g)/CAS No.2933938-46-4 is a dual inhibitor of Janus kinase 2 (JAK2) and microtubule. Tubulin/JAK2-IN-1 has potent antiproliferative activity against the cancer cells.	price>
R-C-645	CP945598（Otenabant ） cas:686344-29-6	Otenabant is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM,exhibits 10,000-fold greater selectivity against human CB2 receptor.	price>
R-R-2345	Tyk2-IN-8 CAS No.2704587-24-4	Tyk2-IN-8/CAS No.2704587-24-4 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease.	price>
R-C-646	GW9508 cas:885101-89-3	GW 9508 is a cell-permeable aminophenylpropanoate that acts as a potent and selective agonist for the G-protein coupled receptor(GPCR)GRP40/FFA1 receptor (EC50 ?50 nM)with reduced activity towards family members GRP120 (EC50?3.5 μM), GRP41/GRP43 (EC50>50 μM),as well as a panel of eight other free fatty acid (FFA) and prostaglandin receptors.	price>
R-R-2346	Filgotinib-d4 CAS No.2041095-50-3	Filgotinib-d4/CAS No.2041095-50-3 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.	price>
R-C-647	CI994 cas:112522-64-2	Tacedinaline(N-acetyldinaline)is an inhibitor of the histone deacetylase(HDAC) with IC50s of 0.9,0.9,1.2μM for recombinant HDAC 1,2 and 3 respectively.	price>
R-R-2347	LFM-A13 CAS No.62004-35-7	LFM-A13/CAS No.62004-35-7 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM. LFM-A13 has antiproliferative activity and anticancer activity. LFM-A13 can be used in cancer-related research.	price>
R-C-648	AT7519HCL cas:902135-91-5	AT7519 Hydrochloride is a potent inhibitor of CDKs,with IC50s of 210,47,100,13, 170,and <10 nM for CDK1,CDK2,CDK4 to CDK6,and CDK9,respectively.	price>
R-R-2348	(3R,4S)-Tofacitinib CAS No.1092578-46-5	(3R,4S)-Tofacitinib/CAS No.1092578-46-5 is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.	price>
R-C-649	StemRegenin 1 (SR1) CAS No. 1227633-49-9	StemRegenin 1(SR1)is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).	price>
R-R-2349	Fosifidancitinib CAS No.1237168-58-9	Fosifidancitinib/CAS No.1237168-58-9 is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases.	price>
R-C-650	KI8751 cas:228559-41-9	Ki8751 is a cell-permeable quinolyloxyphenyl-urea compound that acts as a Flk-1 (VEGFR-2)-selective inhibitior in both cell-based and cell-free assays.	price>
R-R-2350	Nimucitinib CAS No.2740557-24-6	Nimucitinib/CAS No.2740557-24-6 is a Janus kinase (JAK) inhibitor.	price>
R-C-651	Rociletinib (CO-1686) cas:1374640-70-6	Rociletinib(CO-1686,AVL-301)is an irreversible,mutant-selective EGFR inhibitor with Ki of 21.5 nM and 303.3 nM for EGFRL858R/T790M and EGFRWT in cell-free assays,respectively.	price>
R-R-2351	(Rac)-Ruxolitinib-d9 CAS No.2469553-67-9	(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9)/CAS No.2469553-67-9 is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor.	price>

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