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| Catalog | name | Description | price |
|---|---|---|---|
| R-C-941 | mPEG5K-b-PDPA17K | Block copolymer micelles are usually formed by self-assembly of amphiphilic block copolymers in aqueous media.Hydrophilic and hydrophobic blocks form shell and core micelles,respectively.Methoxypolyethylene glycol(MPEG)-b-Poly(2-diisopropylamino)ethyl methacrylate(PDPA)block copolymer was synthesized by atom transfer radical polymerization of 2-bromoisobutyl bromide and MPEG in the presence of triethylamine catalyst.Atom transfer radical polymerization of diisopropylethyl methacrylate (diisopropylethyl ethyl methacrylate) was carried out in DMF at 70℃ with artificial neural network(ANN) and N,pentamethyldiethylenetriamine-copper bromide catalyst system.The pH induced micellization-decellularization was studied by fluorescence method and pyrene probe. | price> |
| R-R-2641 | Cinacalcet hydrochloride CAS No.364782-34-3 | Cinacalcet hydrochloride (AMG-073 hydrochloride)/CAS No.364782-34-3 is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment. | price> |
| R-C-942 | Peptide modified hollow cus wrapped plasmid and cisplatin | Polypeptides have a significant structural advantage,that is,they can be synthesized by solid-phase synthesis or biosynthesis without affecting the original functional polypeptides.New functional polypeptides can be introduced into one or both ends of polypeptides to obtain multifunctional fusion peptides. Cisplatin is an anticancer drug containing platinum, which is orange or yellow crystalline powder,slightly soluble in water and easily soluble in dimethyl Formamide can be gradually converted into trans and hydrolyzed in aqueous solution. | price> |
| R-R-2642 | Evocalcet CAS No.870964-67-3 | Evocalcet (KHK7580)/CAS No.870964-67-3 is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism. | price> |
| R-C-943 | Rhodamine B labeled calcium carbonate nanoparticles(100nm) | Rhodamine B is a synthetic chemical and a dye.It is often dissolved in water and used as a tracer dye to determine the speed and direction of water flow. Rhodamine dye is also widely used in fluorescence microscopy,flow cytometry, fluorescence related spectroscopy and enzyme-linked immunosorbent assay.Nano calcium carbonate is also called ultrafine calcium carbonate.The most mature application industry of nano calcium carbonate is plastic industry,which is mainly used in high-grade plastic products. | price> |
| R-R-2643 | Calhex 231 hydrochloride CAS No.2387505-78-2 | Calhex 231 hydrochloride/CAS No.2387505-78-2 is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment. | price> |
| R-C-944 | DSPE-PEG2000-PPI | Pyrophosphate(PPI)is an anion with important biological functions,which participates in many energy conversion and metabolism processes in organisms. PPI is the product of hydrolysis of adenosine triphosphate in living cells,and its stable metabolic process ensures the normal operation of biological functions.Under the catalysis of DNA polymerase,PPI is closely related to DNA replication,genetic information processing and other processes. | price> |
| R-R-2644 | NPS-2143 hydrochloride CAS No.324523-20-8 | NPS-2143 hydrochloride (SB-262470A hydrochloride)/CAS No.324523-20-8, an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor. | price> |
| R-C-945 | PLGA10K-PEG2K-Cys-Arg-Glu-Lys-Ala(CREKA) | Cys-Arg-Glu-Lys-Ala(CREKA)sequence has been identified as a tumor homing peptide,which can effectively bind to coagulation plasma protein.The results have been compared with the reported separation of CREKA(peptide without dye). It is found that fluorescein affects the energy distribution of the minimum energy conformation,and the repulsive spatial interaction produced by the dye shifts the energy distribution of the minimum energy conformation to a higher energy value. | price> |
| R-R-2645 | Tecalcet Hydrochloride CAS No.177172-49-5 | Tecalcet Hydrochloride (R 568 Hydrochloride)/CAS No.177172-49-5, an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca2+. | price> |
| R-C-946 | Quercetin@IrSx-polyethylene glycol-Chlorin E6 | Quercetin is a kind of flavonol which is widely distributed in the plant kingdom and has a variety of biological activities.Quercetin can resist free radicals, complex or capture free radicals,prevent lipid peroxidation; can directly inhibit tumor,effectively play the role of anti-cancer;it also has strong biological activity in antibacterial,anti-inflammatory,anti allergic,and prevention of diabetic complications. | price> |
| R-R-2646 | Ligustroflavone CAS No.260413-62-5 | Ligustroflavone/CAS No.260413-62-5, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice. | price> |
| R-C-947 | Pyruvic acid-FITC | Pyruvic acid, also known as a-oxopropanoic acid,is an organic compound with the chemical formula of c3h4o3 and the structure of ch3cocooh.It is an important intermediate in the sugar metabolism of all biological cells and the mutual transformation of many substances in the body.As a basic chemical raw material, pyruvic acid is widely used in various fields such as chemistry, pharmacy,food, agriculture and environmental protection because of its active ketone and carboxyl group.Fluorescein isothiocyanate(FITC)is a derivative of fluorescein, which is widely used in flow cytometry and other fields.FITC is reactive to nucleophiles including amines and sulfhydryls on proteins.The excitation and emission peak wavelength of FITC is about 495 nm/519 nm,which makes it green. Like most fluorescent dyes,it is prone to photobleaching. | price> |
| R-R-2647 | Upacicalcet sodium CAS No.2052969-18-1 | Upacicalcet sodium/CAS No.2052969-18-1 is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT). | price> |
| R-C-948 | Mandelic acid-FITC | Mandelic acid and its derivatives are metabolites of epinephrine and norepinephrine by monoamine oxidase and catecholamine-O-methyltransferase in vivo.There is a chiral carbon atom in mandelic acid molecule,so there are(R)and (s) enantiomers.Fluorescein isothiocyanate(FITC)is a derivative of fluorescein, which is widely used in flow cytometry and other fields.FITC is reactive to nucleophiles including amines and sulfhydryls on proteins.The excitation and emission peak wavelength of FITC is about 495 nm/519 nm,which makes it green. Like most fluorescent dyes,it is prone to photobleaching. | price> |
| R-R-2648 | Calcium-Sensing Receptor Antagonists I CAS No.478963-79-0 | Calcium-Sensing Receptor Antagonists I/CAS No.478963-79-0 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | price> |
| R-C-949 | Salicylic acid-FITC | Salicylic acid is soluble in ethanol,ether,chloroform,benzene,acetone and turpentine,but not soluble in water.It exists in willow bark,white pearl leaves and Betula platyphylla.Salicylic acid is a kind of organic acid,which can be metabolized by salicin.It is widely used in organic synthesis and is also a plant hormone.Fluorescein isothiocyanate(FITC)is a derivative of fluorescein, which is widely used in flow cytometry and other fields.FITC is reactive to nucleophiles including amines and sulfhydryls on proteins.The excitation and emission peak wavelength of FITC is about 495 nm/519 nm,which makes it green. Like most fluorescent dyes,it is prone to photobleaching. | price> |
| R-R-2649 | SB-423562 CAS No.351490-27-2 | SB-423562/CAS No.351490-27-2 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research. | price> |
| R-C-950 | p-SCN-BnNOTA | The chelating agents except p-SCN-BnNOTA in plasma were very stable,and the dissociation rate of Cu2+was less than 9% at 96 H.The immune response varies with the choice of chelating agents,especially the antiserum of Cu2+nota KLH conjugate.Compared with other chelating agents,p-SCN-BnNOTA has a significant advantage in the preparation of antibody. | price> |
| R-R-2650 | GSK3004774 CAS No.2138814-32-9 | GSK3004774/CAS No.2138814-32-9 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR. | price> |

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