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R-R-2840 Glucagon receptor antagonists-2 CAS No.202917-18-8 Glucagon receptor antagonists-2/CAS No.202917-18-8 is a highly potent glucagon receptor antagonist. price>
R-C-1141 CL-387785 (EKI-785) CAS :194423-06-8 CL-387785,also known as EKI-785,is a n irreversible inhibitor of EGF-receptor (EGFR)kinase activity in vivo(IC50=250-490 pM).CL-387785 covalently bound to EGF-R.It also specifically inhibited kinase activity of the protein(IC50 =370+/-120 pM),blocked EGF-stimulated autophosphorylation of the receptor in cells(ic50 approximately 5 nM),inhibited cell proliferation(IC50=31-125nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2,and profoundly blocked the growth of a tumor that overexpresses EGF-R in nude mice(when given orally at 80 mg/kg/day for 10 days,daily). price>
R-C-2841 mPEG-PDLLA-PLL Methoxy poly(ethylene glycol)-poly(L-lactide)-poly(L-lysine)polyethylene glycol polylactic acid polylysine triblock,three polymer materials are crosslinked to form triblock copolymer α-Polylysine is commonly used to coat tissue culture vessels as an adhesion factor to improve cell adhesion.This phenomenon is based on the interaction between positively charged polymers and negatively charged cells or proteins. price>
R-R-2841 GLP-1R modulator L7-028 CAS No.2648317-95-5 GLP-1R modulator L7-028/CAS No.2648317-95-5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM). price>
R-C-1142 GW2580 CAS:870483-87-7 GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM.GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling. price>
R-C-2842 DSPE-TK-Decitabine As a specific DNA methyltransferase inhibitor,decitabine can reverse the DNA methylation process,induce tumor cells to differentiate into normal cells or induce tumor cell apoptosis. price>
R-R-2842 GLP-1R modulator C16 CAS No.875005-43-9 GLP-1R modulator C16/CAS No.875005-43-9 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 8.43 ± 3.82 μM). price>
R-C-1143 TRX818 CAS:1256037-58-7 TRX-818 is a new,potent and multi-targeted anti-cancer agent in numerous human cancer cell lines. price>
R-C-2843 DSPE-PEG2K-PBA 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower, so the drug stability is better, even by hemodilution, can maintain the integrity of the micelle particle,has certain targeting, easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.Benzeneboronic acid was used as boric acid component in Suzuki diaryl cross coupling study;Used for still and Suzuki cross coupling reaction price>
R-R-2843 GLP-1 receptor agonist 2 CAS No.2230197-64-3 GLP-1 receptor agonist 2/CAS No.2230197-64-3 is a glucagon-like peptide-1 receptor (GLP-1R) agonist. price>
R-C-1144 URMC-099 CAS:1229582-33-5 URMC-099 is an orally bioavailable,brain penetrant mixed lineage kinase (MLK)inhibitor with IC50 of 19 nM,42 nM,14 nM,and 150 nM,for MLK1,MLK2,MLK3,and DLK,respectively,and also inhibits LRRK2 activity with IC50 of 11 nM.URMC-099 also inhibits ABL1 with IC50 of 6.8 nM.URMC-099 induces autophagy. price>
R-C-2844 DSPE-SS-Mercaptopyridine Mercaptopyridine and pyridinrthiols have two isomers.2-Ryukyipizha is soluble in water,ethanol,benzene and chloroform.Its N-oxide melting point is B7. price>
R-R-2844 LSN3318839 CAS No.2764704-18-7 LSN3318839/CAS No.2764704-18-7 is an orally efficacious positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R). price>
R-C-1145 3-Cyano-7-ethoxycoumarin CAS:117620-77-6 3-Cyano-7-ethoxycoumarin is a fluorogenic substrate suitable for the continuous determination of cytochrome P450 mixed-function monooxygenases.It is a fluorescent probe useful in microsomal dealkylase studies. price>
R-C-2845 Azithromycin limonamide tobramycin Azithromycin is a semi synthetic 15 membered macrolide antibiotic.White or off white crystalline powder;Odorless and bitter;Slightly hygroscopic.Tobramycin is highly effective against Gram-negative bacteria,especially Pseudomonas aeruginosa. price>
R-R-2845 TT-OAD2 CAS No.2382719-60-8 TT-OAD2/CAS No.2382719-60-8 is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM. TT-OAD2 has the potential for diabetes treatment. price>
R-C-1146 BIX01294 HCl CAS:1392399-03-9 BIX01294 is a potent chemical inhibitor of G9a methyltransferase that catalyzes the mono-and di-methylation of the lysine 9 residue of histone H3.BIX01294 suppresses osteoclast differentiation on mouse macrophage-like Raw264.7cells. BIX01294 enhances the cardiac potential of bone marrow cells. price>
R-C-2846 glycyrrhetic acid-PEG-hyd-PLGA Cell information transmission and gene expression Glycyrrhizic acid has inhibitory effect on experimental animal malignant tumor bacteria induced by a variety of carcinogens Glycyrrhetinic acid also has the effect of antiviral infection,and EB virus and HIV infection are all inhibited. price>
R-R-2846 GLP-1R modulator C5 CAS No.421578-93-0 GLP-1R modulator C5/CAS No.421578-93-0 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM). price>
R-C-1147 ML204 CAS:5465-86-1 ML204 is a novel,potent,and selective TRPC4 channel inhibitor with apparent IC50 values of about 1 μM in fluorescent intracellular Ca2+ assays and about 3 μM in whole-cell voltage clamp experiments.It exhibits some selectivity within the TRPC subfamily of channels and higher selectivity against other TRP channels and non-TRP channels. price>