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R-C-2868 Black phosphorus nano flake (Thickness 2-3nm) Black phosphorus material can be used as an efficient photosensitizer,which can produce a large amount of singlet oxygen and can be used in photodynamic therapy.Black phosphorus itself has no toxicity to a variety of cells. After polyethylene glycol(PEG)is modified by electrostatic adsorption,the oxidation of black phosphorus can be effectively reduced and the stability can be significantly improved.It can not only improve the biocompatibility of the material,but also facilitate the further functional modification of the material.Black phosphorus nano flakes can produce local high heat under 808 nm laser irradiation.On the one hand,they can be used for photothermal therapy of tumors,on the other hand,they can also drive the release of drugs. price>
R-R-4538 Bizelesin CAS No.129655-21-6 Bizelesin (NSC 615291; U-77779)/CAS No.129655-21-6 is an AT-specific DNA alkylating agent that can generate DNA interstrand crosslinks, effectively inhibit DNA replication, and has potential anticancer activity. price>
R-C-2869 DSPE-PEG-VCAM1 Vascular cell adhesion protein 1(VCAM1)is also known as CD106,INCAM-100 and L1CAM,is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily.VCAM1/CD106 contains 7 Ig-like C2-type(immunoglobulin-like) domains.1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors. Suitable for the development of long circulating liposomes. price>
R-R-4539 PR-104 CAS No.851627-62-8 PR-104/CAS No.851627-62-8 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A. price>
R-C-2870 DSPE-PEG2K-Up conversion (red green light) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting, easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.Upconversion luminescence refers to that the material is excited by low-energy light and emits high-energy light,when excited by light with long wave length and low frequency,the material emits light with long wave length and high frequency. price>
R-R-4540 2-Iodoacetamide-d4 CAS No.1219802-64-8 2-Iodoacetamide-d4/CAS No.1219802-64-8 is the deuterium labeled 2-Iodoacetamide. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics. price>
R-C-2871 DSPE-PEG2K-Up conversion (pure red light) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors. Suitable for the development of long circulating liposomes.Upconversion luminescence refers to that the material is excited by low-energy light and emits high-energy light,that is,when excited by light with long wave length and low frequency,the material emits light with long wave length and high frequency. price>
R-R-4541 Miriplatin CAS No.141977-79-9 Miriplatin (SM-11355)/CAS No.141977-79-9 is a chemotherapy agent which belongs to the class of alkylating agents. price>
R-C-2872 DSPE-PEG-RYYRITY Modified fluorescent FAM 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution, can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.Fluorescent markers are also widely used in protein function research,drug screening and other fields. price>
R-R-4542 Tesirine intermediate-1 CAS No.1430738-05-8 Tesirine intermediate-1/CAS No.1430738-05-8 is the intermediate of Tesirine (HY-128952). Tesirine (SG3249), a pyrrole benzodiazepine (PBD) dimer, is a DNA small channel crosslinker with strong cytotoxicity. Tesirine can be used to synthesize Antibody-Drug Conjugates (ADCs), the warhead component of the payload is SG3199 (HY-101161), which has strong anticancer cell activity. price>
R-C-2873 PC(MSPC) We can provide conventional phospholipid monomers,PEG phospholipids,modified phospholipids,fluorescent labeled phospholipids,polymer phospholipids, phospholipid coupling inorganic nano materials and microspheres,monodisperse small molecule peg phospholipid coupling products. price>
R-R-4543 (S)-Seco-Duocarmycin SA CAS No.152785-82-5 (S)-Seco-Duocarmycin SA/CAS No.152785-82-5 is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates. price>
R-C-2874 phosphatidylcholine Liposome 100NM Phospholipids include natural phospholipids and synthetic phospholipids.The structure of phospholipids is characterized by a hydrophilic group composed of one phosphate group and one quaternary ammonium group,and a lipophilic group composed of two longer hydrocarbon groups.Natural phospholipids are mainly lecithin (phosphatidylcholine,PC),which comes from egg yolk and soybean. price>
R-R-4544 Duocarmycin Analog CAS No.372954-15-9 Duocarmycin Analog/CAS No.372954-15-9 is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin. price>
R-C-2875 Allen phosphate-stearic acid Alendronate is a bone metabolism regulator,which can inhibit the activity of osteoclasts and inhibit bone resorption.Stearic acid,octadecanoic acid, produced by oil hydrolysis,is mainly used to produce stearate. price>
R-R-4545 Temozolomide-d3 CAS No.208107-14-6 Temozolomide-d3/CAS No.208107-14-6 is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects. price>
R-C-2877 Paclitaxel-Monophosphoric acid Paclitaxel is a natural antitumor drug that can stabilize the polymerization of tubulin.Paclitaxel can lead to mitotic arrest and apoptosis,and eventually lead to cell death.5- adenine nucleotide,or adenylate,is a nucleotide found in ribonucleic acid(RNA). price>
R-R-4546 Cyclophosphamide-d4 CAS No.173547-45-0 Cyclophosphamide-d4/CAS No.173547-45-0 is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant. price>
R-R-4547 Carboplatin-d4 Carboplatin-d4 is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent. price>
R-C-2878 PTX-Diphosphate Bisphosphonates are stable analogues of pyrophosphonate molecules.After osteoclasts accumulate in mineralized bone matrix,they lead to bone resorption through enzymatic hydrolysis.Bisphosphonates can inhibit osteoclast mediated bone resorption,inhibit the maturation of osteoclasts,inhibit the function of mature osteoclasts and the aggregation of osteoclasts at the site of bone resorption,and inhibit the diffusion,infiltration and adhesion of tumor cells to bone matrix. price>