Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-C-1659	MK-1064 CAS：1207253-08-4	MK-1064 is a selective orexin 2 receptor antagonist(2-SORA)for the research of insomnia.	price>
R-C-1677	PF-04418948 CAS：1078166-57-0	PF-04418948 is a novel,potent and selective prostaglandin EP2 receptor antagonist.PF-04418948 inhibited prostaglandin E(2)(PGE(2))-induced increase in cAMP in cells expressing EP(2)receptors with a functional K(B)value of 1.8nM.	price>
R-R-3377	Facinicline hydrochloride CAS No.677305-02-1	Facinicline hydrochloride (RG3487 hydrochloride)/CAS No.677305-02-1 is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM.	price>
R-R-3378	Revexepride CAS No.219984-49-3	Revexepride/CAS No.219984-49-3 is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease.	price>
R-R-3379	Relenopride hydrochloride CAS No.1221416-42-7	Relenopride (YKP10811) hydrochloride/CAS No.1221416-42-7 is a specific and selective 5-HT4 receptor agonist (Ki=4.96 nM). Relenopride hydrochloride has 120-fold and 6-fold lower affinity, respectively, for 5-HT2A (Ki=600 nM) and 5-HT2B receptors (Ki=31 nM) than for 5-HT4. Relenopride hydrochloride increases gastrointestinal (GI) motility.	price>
R-C-1680	Carteolol hydrochloride CAS：51781-21-6	Carteolol hydrochloride(OPC-1085 hydrochloride)is a non-selective beta blocker used to treat glaucoma.	price>
R-R-3380	TC-2153 CAS No.1381769-23-8	TC-2153/CAS No.1381769-23-8 is a selective inhibitor of striatal-enriched protein tyrosine phosphatase (STEP), with psychotropic activity and low acute toxicity. TC-2153 increases the expression of brain-derived neurotropic factor (BDNF) in the brain. And it decreases MAOA and 5-HT1A receptors mRNA level in midbrain. TC-2153 also inhibits 5-HT2A receptor-mediated signaling.	price>
R-R-3381	(R)-Praziquantel-d11 CAS No.1399880-38-6	(R)-Praziquantel-d11/CAS No.1399880-38-6 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer.	price>
R-C-1682	SQ22536 CAS：17318-31-9	SQ22536(9-(tetrahydrofuran-2-yl)-9h-purin-6-amine)is an inhibitor of adenylyl cyclase with an IC50 of 1.4μM.It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.	price>
R-R-3382	Clozapine-d8 CAS No.1185053-50-2	Clozapine-d8/CAS No.1185053-50-2 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors.	price>

...

163