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R-C-2772 DMP 777 CAS:157341-41-8 DMP-777(L 694458)is a potent and orally active Leukocyte elastase(HLE)inhibitor.Oral dosing with DMP 777 caused a rapid increase in serum gastrin levels and severe hypochlorhydria.DMP 777 inhibited aminopyrine accumulation into rabbit parietal cells stimulated with either histamine or forskolin. price>