Product phospholipids -phospholipid-peg-customization

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Catalog	name	Description	price
R-DS-0065	LyP-1-PEG3400-DSPE	Cyclopeptide LyP-1 modified liposomes:polypeptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs. It has also been proved by experiments that it can enhance the targeting specificity of drugs,enhance the targeted absorption of drugs,improve the anti-tumor effect,and at the same time,it can improve the original insoluble properties of some small molecule drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-DS-0066	c(RGDyK)-pHA-PEG-DSPE	Peptide mediated targeting drug nanopreparation is an active targeting drug preparation which introduces peptide targeting molecules onto the surface of nano carriers.It can increase the amount of drugs reaching tumor tissue and tumor cells,and achieve the goal of effective treatment of tumor.c(RGDyK) was used as a model peptide targeting molecule,which could be modified on the surface of liposomes.The immunogenicity and related mechanism of peptide mediated targeting nanoparticles were systematically studied.	price>
R-DS-0067	MC-DA7R-PEG-DSPE	MC-DA7R-PEG-DSPE liposome delivery system can transport BBB and BBTB, target glioma cells,stem cells and tumor neovascularization.After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-DS-0068	MC-PEG-DSPE	After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-DS-0069	DA7R-PEG-DSPE	After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-DS-0070	DSPE-PEG-M2pep(YEQDPWGVKWWY)	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.The liposome can not stay in the tumor site for a long time after intravenous injection,but the targeted liposome prepared by connecting peptide on the surface of liposome can reach the target site immediately after intravenous injection and stay in the tumor site for a long time. The drug released from the liposome can improve the therapeutic effect of tumor.Polyethylene glycol phospholipid is an excellent material to form liposomes,which can be used for gene transfection, vaccine delivery,drug delivery and targeted drug use.	price>
R-DS-0071	GLP-1-PEG-DSPE	Glucagon like peptide-1 (GLP-1) is a kind of brain gut peptide secreted by ileal endocrine cells.It is mainly used as the target of type 2 diabetes drugs.PEG modification makes the previously insoluble peptides less soluble and highly mobile.PEG modification can reduce the filtration of drugs by kidney,reduce its pyrogen,reduce the digestion of protease, and enhance its transport capacity by protecting the body immune system.GLP-1 has two Lys located in the inactive site, which provides great flexibility for modification.	price>
R-DS-0072	HP2-PEG2000-DSPE	HER2,also known as c-erb2,consists of 922 adenine,1382 cytosine,1346 guanine and 880 thymine.HER2 protein mediated signal transduction pathways include Ras/Raf/mitogen activated protein kinase (MAPK),phosphatidylinositol 3-hydroxykinase (PI3K)/Akt pathway,signal transduction and transcriptional activation (STAT) pathway and PLC pathway.	price>
R-DS-0073	CPPs-PEG-DSPE	Polypeptide modified peg-dspe functional branches were synthesized by the specific reaction between maleimide and thiol group.Targeted CPPs modified nano liposomes were constructed by thin film dispersion method.The physicochemical properties in vitro,including average particle size,surface potential,entrapment efficiency,polydispersity index and in vitro release rate,were studied by laser particle size analyzer and ultraviolet fluorescence spectrophotometry.	price>
R-DS-0074	DSPE-PEG-CGKRKb	As a drug carrier,liposomes are widely used in tumor drug delivery.Liposome is a kind of ultramicro drug carrier with structure and composition similar to biofilm.Because of its biocompatibility,cell affinity and targeting properties, liposomes have been widely used in anti-tumor.	price>

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