Product phospholipids -phospholipid-peg-customization

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Catalog	name	Description	price
R-DS-0080	DSPE-PEG-CD133	Tumor stem cells have become a new target for drug delivery.Tumor stem cells express specific markers on their surface,and CD133 is highly expressed in glioma stem cells.In order to achieve the goal of drug delivery,TR peptide specifically binding to CD133 was modified to drug delivery system.	price>
R-DS-0081	γ-Folate-PEG-DSPE	α-andγ-folate-cys were prepared by solid-phase synthesis of peptides.α-and γ-folate-peg-dspe were prepared by the specific reaction between thiol group and mal of Cys.The purity and structure of α-andγ-folate-peg-dspe were characterized by HPLC and 1H-NMR.	price>
R-DS-0082	γ-Folate-PEG-DSPE-DOX	Doxorubicin (DOX) is widely used in the treatment of breast cancer,bladder cancer and other solid tumors because of its wide anti-tumor spectrum,exact curative effect and low price.Because of the advantages of high selectivity to tumor tissues,less distribution in normal tissues and effective increase of drug circulation time in vivo,macromolecular tumor targeting drugs have become a hot spot in new drug research and development.	price>
R-DS-0083	Tf-PEG-DSPE	Transferrin receptor (TFR) is a kind of glycoprotein which mediates iron absorption through the interaction with transferrin.In normal cells,the expression level of receptor is low. Due to the increasing demand for iron in rapidly growing tumor cells and the effective targeting function of transferrin receptor,the cross-linking of transferrin and tumor therapeutic drugs can not only improve the specific binding ability of drugs,but also improve the therapeutic effect.	price>
R-DS-0084	DSPE-PEG2000-ACPP	Liposome is a kind of ultramicro drug carrier with structure and composition similar to biofilm.Because of its biocompatibility,cell affinity and targeting properties,liposomes have been widely used in anti-tumor.Active targeting liposomes include immunoliposomes,receptor-mediated liposomes and glycosylated liposomes.	price>
R-DS-0085	pCPP-PEG-DSPE(CKRRMKNvocWKNvo0cKNvoc)	PCPP could increase the titers of IgM,IgG and IgG1 of influenza antigen by at least 10 times.The amount of PCPP adjuvant was positively correlated with the molecular weight of the polymer.	price>
R-DS-0086	DSPE-PEG2000-YSA	The preparation and characterization of siRNA loaded ysa peptide modified nanostructured lipid carriers (siRNA/ysa-nlc) were studied.Dspe-peg2000-ysa was prepared by the reaction of ysa and dspe-peg2000 mal;NLC was prepared by melt ultrasonic method;the surface of NLC was modified by synthesized dspe-peg2000-ysa to prepare ysa-nlc,which was compounded with siRNA,The optimal amount of dspe-peg2000-ysa was screened by MCF-7 cells,and the optimized siRNA/ysa-nlc was characterized.	price>
R-DS-0087	DSPE-PEG-ATWLPPR	DSPE co rotating polyethylene glycol is a kind of phospholipid and polyethylene glycol.The combination of glycol has hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.Pegylated cationic liposomes were modified with D4,a small molecular peptide ligand targeting epidermal growth factor receptor (EGFR),and its effect on transfection efficiency of tumor cells was found by observing the improvement of plasmid DNA and siRNA.	price>
R-DS-0001	DSPE-PEG_(2000)-RVG-15（YTIWCDIFTNSRGKR）	Rabies virus glycoprotein derived peptide 15 (rvg-15) peptide was linked to polyethylene glycol phosphatidylethanolamine (peg-dspe),and a brain targeting vector,polyethylene glycol phosphatidylethanolamine(DSPE-PEG),was synthesized_ (2000)-rvg-15)can solve the bottleneck problem of small molecule chemical drugs entering the brain and reduce the systemic side effects.	price>
R-DS-0088	DSPE-PEG2000-CpG	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>

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